Speed up your efficiency and boost your lab throughput with the power of microwaves.
Despite advances in technology, cleavage and deprotection can bottleneck your lab's productivity.
The Milestone wavePREP system redefines oligonucleotide processing by combining microwave heating with a robust stainless-steel reactor for precise temperature control.
The Milestone wavePREP system redefines oligonucleotide processing by combining microwave heating with a robust stainless-steel reactor for precise temperature control.
By conducting cleavage and deprotection simultaneously in the gas phase, wavePREP cuts down the steps needed, bypassing the evaporation process, boosting yields, and enhancing your oligo discovery process and scaling up to manufacturing.
AUTOMATED LOADING/ DRAINING STATION
The system features a dedicated pump
designed for the automated addition and
drainage of reagents. This eliminates the need
for direct operator exposure to chemicals,
as the process is controlled by software and
performed automatically.
HOLDERS
Available for different supports such as well
plates and columns, the holders offer maximum
flexibility to meet any requirement.
TEMPERATURE & PRESSURE SENSOR
The yield of oligos production greatly depends
on the cleavage and deprotection processes.
The precise temperature and pressure
sensors ensure optimal control of the reaction
procedure, resulting in maximized yields.
STAINLESS-STEEL CHAMBER
The reactions occur within a sealed stainlesssteel
reactor, providing secure handling of
pressure throughout the process.
USER INTERFACE
The user interface allows for complete control
and tracking of all reaction parameters and
functionalities. It is designed in full compliance
with GMP regulations, ensuring adherence to
quality standards.
Struggling with time-consuming and underperforming cleavage and deprotection in oligonucleotide synthesis?
Milestone’s wavePREP addresses the bottleneck associated to the C&D steps. Our stainless-steel microwave reactor accelerates processes to as little as 2 hours, enhancing safety and process control through precise real-time monitoring, allowing full tracking of process parameters.
CLEAVAGE AND DEPROTECTION INTO A SINGLE STEP
Despite advances in technology, these steps can bottleneck your lab's productivity. Milestone’s wavePREP system addresses these challenges head-on. Our stainless-steel microwave reactor accelerates processes to just 2 hours, enhancing safety and process control through precise real-time monitoring, allowing full track of the manufacturing parameters.
A strategy to minimize the risk of harmful, volatile solvents exposure of operators.
FAST
AND AUTOMATED
wavePREP enables simultaneous oligonucleotide cleavage and deprotection in as little as 90 minutes, saving up to 95% of time compared to traditional methods. The system significantly improves the efficiency of the laboratory workflow by automating and software controlling various steps, including the lowering of well plates into the reactor, reagent addition, chamber draining and venting. With wavePREP, laboratories can achieve faster and more streamlined processes, optimising productivity.
HIGH
PRODUCTIVITY
The combination of shorter
processing time and higher
yields achieved with wavePREP
results in superior productivity.
This versatile system can be used
with well plates OR columns to accommodate
various needs. With its flexible configurations and
large reactor capacity, wavePREP can process up
to 6 well plates in just 90 minutes. Furthermore,
there is no need to perform an evaporation step
after wavePREP C&D, shorteing even more
the overall process lenght.
PRODUCT
YIELDS
The conventional postsynthesis
approach involves
multiple critical steps to achieve
superior yields. However, the
wavePREP approach eliminates
some of these crucial steps and operates within
a controlled environment. By doing so, it ensures
significantly higher yields compared to traditional
approaches. With wavePREP, laboratories
can expect improved efficiency and increased
productivity, leading to enhanced overall product
yields.
SUPERIOR
SAFETY
wavePREP prioritizes
operational safety through its
robust stainless-steel reactor
and adherence to the highest
manufacturing standards. The
system's workflow, facilitated by the automated
pump, eliminates the need for direct handling of
chemicals, minimizing operator exposure. The
temperature and pressure sensors ensure a fully
controlled process, further enhancing safety
measures. An added benefit is the elimination
of the reagents evaporation step, leading to an
improvement of the work environment.
Questions? We've got answers
Milestone™ Srl
Via Fatebenefratelli 1/5 - 24010 Sorisole (BG) - Italy
Phone: +39 035.573857 | Fax: +39 035.575498
Via Fatebenefratelli 1/5 - 24010 Sorisole (BG) - Italy
Phone: +39 035.573857 | Fax: +39 035.575498
Milestone™ Srl
Via Fatebenefratelli 1/5 - 24010 Sorisole (BG) - Italy
Phone: +39 035.573857 | Fax: +39 035.575498
Via Fatebenefratelli 1/5 - 24010 Sorisole (BG) - Italy
Phone: +39 035.573857 | Fax: +39 035.575498